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Inside a modern review, we reported the identification as well as the characterization of a brand new atypical opioid receptor with exclusive destructive regulatory Houses to opioid peptides.1 Our success confirmed that ACKR3/CXCR7, hitherto often known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, can be a broad-spectrum scav